Hello @Boy-Lenssen ,
list itemDIs are a galvanically isolated so unless the voltage and current will stay in the limits, you should be OK
Digital outputs & analog inputs and outputs are coupled together to common ground. So a there could be a risk of potential damage to these components when you are off the limits.
But do not worry the device is designed to provide maximum reliability when installed in the standard installation environment. And yes, replacing the device in case something goes wrong is the easiest and cheapest solution.